Search results for "Phosphate-buffered solution"

showing 2 items of 2 documents

Facile and efficient chemical functionalization of aliphatic polyesters by cross metathesis

2016

International audience; An effective preparation of new tailor-made macromolecular materials via a combination of two (atom-efficient) catalytic transformations is reported. First, new aliphatic polyesters with alternated composition have been prepared using a salen aluminum catalyst system. Next, the pendant vinyl moieties in those copolymers have been selectively transformed into various functional groups by metathesis in the presence of homogeneous Grubbs catalysts. The latter metathesis reaction has been optimized in terms of catalytic activity and selectivity, to define the conditions for an effective and safe procedure that does not affect the macromolecular architecture. All polymer …

plga microspheresphosphate-buffered solutionin-vivo degradationPolymers and PlasticsBioengineeringmolecular-weight poly(l-lactide)010402 general chemistryMetathesis01 natural sciencesBiochemistry[ CHIM ] Chemical SciencesCatalysisacid) microspheresCopolymerSalt metathesis reactionenzymatic degradation[CHIM]Chemical SciencesOrganic chemistryRing-opening metathesis polymerisationcyclic anhydrides010405 organic chemistryChemistryring-opening copolymerizationOrganic Chemistryrenewable resources0104 chemical sciencesPolyester[ CHIM.POLY ] Chemical Sciences/Polymers[CHIM.POLY]Chemical Sciences/Polymersbiodegradable polymersSelectivityAcyclic diene metathesis
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Beyond Biodegradability of Poly(lactic acid): Physical and Chemical Stability in Humid Environments

2017

International audience; Poly(lactic acid) (PLA) is the most traded biodegradable and biobased material. It is largely used as ecofriendly substitute of conventional plastics. Nevertheless, one of the main limiting factors is its water sensitivity. PLA reacts with water and is hydrolyzed during time, which determines its performance. Limited information related to the hydrolysis mechanism driven by water in vapor state is available in scientific literature. Literature is mainly focused on the effects of water in liquid state. This lack of information is of significant importance, since PLA interacts with water in both phases. This work was aimed to give a full depiction of the chemical and p…

AgingHydrolytic degradationPhosphate-buffered solutionGeneral Chemical EngineeringAmorphous fractions02 engineering and technologyPolylactide010402 general chemistry01 natural sciencesBioplasticHydrolysischemistry.chemical_compoundGlass-transition[SDV.IDA]Life Sciences [q-bio]/Food engineeringEnvironmental ChemistryOrganic chemistryRelative humidityRelative-humidityState of waterPoly(l-lactic acid)Renewable Energy Sustainability and the EnvironmentChemistryHydrolysisAmorphous phase[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringtechnology industry and agricultureGeneral ChemistryBiodegradationequipment and supplies021001 nanoscience & nanotechnology0104 chemical sciencesLactic acidBioplasticLactide copolymersPLADegradation (geology)Chemical stabilityIn-vitro degradation0210 nano-technologyGlass transitionACS Sustainable Chemistry & Engineering
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